Gregory Pincus (EDT) Hormones and Atherosclerosis

Annotation

Hormones and Atherosclerosis covers the proceedings of the conference held in Brighton, Utah on March 11-14, 1958. The book focuses on the role of hormones in atherosclerosis, as well as cholesterol metabolism and biosynthesis, lipogenesis, and lipid transport. The selection first discusses the biosynthesis of cholesterol and aspects of the biosynthesis of cholesterol from mevalonic acid. Discussions focus on components of liver homogenates and coenzymes required for squalene and sterol synthesis from mevalonic acid and preservation of enzymes and microsomes. The text also ponders on the formation and metabolism of bile acids under different conditions and thyroid function, thyroxine analogs, and cholesterol metabolism in rats and rabbits. The book elaborates on the comparison of the participations of fibroblasts and reticuloendothelial cells in the synthesis and metabolism of cortisol and cholesterol and control of aortal lipid metabolism and lipid movement by hormones and vitamins. The manuscript also examines the influence of estrogens on lipids and atherosclerosis in experimental animals and the effect of adrenals, pituitary, liver, and mucopolysaccharides on blood lipids. The selection is a dependable reference for readers interested in the relationship of hormones and atherosclerosis.