Endre A. Balazs (EDT), Roger W. Jeanloz (EDT) Metabolism and Interactions

Annotation

The Amino Sugars: The Chemistry and Biology of Compounds Containing Amino Sugars, Volume IIB: Metabolism and Interactions takes a look at the chemistry, physical chemistry, and biochemistry of naturally occurring and synthetically prepared amino sugars and amino sugar-containing molecules and the critical and interpretative account of the biological and medical importance of these molecules. The selection takes a look at the metabolism of amino sugars, glycosaminoglycans, and glycoproteins, glycopeptides, and glycolipids. Topics include pathways of degradation, energy-utilizing reactions, catabolism, formation of macromolecules, and metabolism of moieties. The text then ponders on the effects of steroid hormones on the glycosaminoglycans of target connective tissues, hexosaminidases, and neuraminidases. The publication elaborates on enzymes degrading glycosaminoglycans, sulfatases of glycosaminoglycans, and activation and inhibition of enzymes by polyanions containing amino sugars. The manuscript also reviews the chemical and physical changes of glycosaminoglycans and glycoproteins caused by oxidation-reduction systems and radiation and interactions between glycoproteins and viruses. The selection is a dependable reference for readers interested in amino sugars.